Characterization and modification of cavitation pattern in shock wave lithotripsy

The temporal and spatial dynamics of cavitation bubble cloud growth and collapse in extracorporeal shock wave lithotripsy (ESWL) is studied experimentally. The first objective is obtaining reproducible cloud patterns experimentally and comparing them with FDTDcalculations. Second, we describe a method to modify the cavitation pattern by timing two consecutive pressure waves at variable delays. It is found that the spatial and temporal dynamics of the cavitation bubble can be varied in large ranges. The ability to control cavitation dynamics allows discussing strategies for improvement of medical and biological applications of shock waves such as cell membrane poration and stone fragmentation.